Bacteriología urinaria asintomática en mujeres diabéticas tipo 2 / Prevalence of asymptomatic bacteriuria in type 2 diabetic women

Background: Urinary tract infection (UTI) is frequent among diabetics, especially women. It may be preceded by asymptomatic bacteriuria. Aim: To study the frequency of asymptomatic bacteriuria in type 2 diabetic women. Patients and methods: Fifty women with type 2 diabetes and 50 non diabetic women were studied. In aseptic conditions, morning midstream urine specimens were obtained for microbiological analysis. The test was repeated in similar conditions during consecutive days. Urine samples were cultured in blood agar, Mac Conkey agar and CPS ID 2. Colony forming units were counted. Asymptomatic bacteriuria was defined as the presence of 100,000 or more colony forming units per ml. Leukocyturia was also quantified. Results: There was microbial growth in 40 percent of samples from diabetic women and 6 percent of samples from controls (p <0.01). Asymptomatic bacteriuria was present in 32 percent of diabetics and 4 percent of controls (p <0.01). E Coli was the most frequently isolated strain, in 55 percent of patients and 100 percent of controls. Klebsiella pneumonió was isolated in 10 percent of diabetics, coagulase negative Staphylococcus in 10 percent, Enterococcus spp in 10 percent and Pseudomonas aeruginosa in 5 percent. Leukocyturia of more than 10 cells per field, was present in 80 percent of diabetic women with positive culture. Women with positive cultures had a longer lasting diabetes than those with negative cultures. There was no association between urine microbiological results and glycosilated hemoglobin, fasting blood glucose, chronic complications of diabetes and treatment received. Conclusions: This study shows a high prevalence of asymptomatic bacteriuria among diabetic women

Estudio clínico y anatomopatológico en cinco casos de vasculitis portadores de anticuerpos anticitoplasmáticos de neutrófilos con patrón citoplasmático / Clinical and anatomopathological study in 5 cases of vasculitis carrying neutrophil anticytoplasmatic antibodies with cytoplasmatic pattern

We report five patients with vasculitis and antineutrophil cytoplasmic antibodies with cytoplasmic pattern. All had severe upper and lower respiratory tract necrotizing lesions. Three had kidney failure due to rapidly progressive glomerulonephritis. The pathological study showed a crescentic glomerulonephritis, a chronic granulomatous inflammation in the lungs and in the nasal mucosa, an acute nonspecific inflammation or a chronic granulomatous inflammation and focal blood vessel fibrinoid necrosis. All patients with simultaneous involvement of lungs and kidneys had high titers of antineutrophil cytoplasmic antibodies. The nomenclature and classification of these diseases is discussed